Description
LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
30-day money-back guarantee
Shipping: 24/48H of Stock Products - 2 to 4 weeks of fresh LOT products.
Customer Reviews
No reviews yet. Be the first to review this product.
No reviews yet.
Please sign in to write a review.
Similar Products
AffiAB® Alkaline Phosphatase Conjugated Affinity Purified anti-Swine IgG (H&L) [Goat] Antibody
Cat# AFG-BMG-3206
$Ask for Quotation