Description
CD352, also known as SLAMF6 (SLAM family member 6) is a type I transmembrane glycoprotein expressed on NK cells, T cells, and B cells, and serves as a coreceptor for them. Besides association of its tyrosine phosphorylated intracellular domain with SH2D1A protein, it associates also with SH2 domain-containing phosphatases, which can modulate the signaling. Multiple CD352 isoforms have been identified.
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