Description
Function: May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. similarity: Contains 1 dilute domain. similarity: Contains 1 Ras-associating domain. subcellular location: Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS. subunit: Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2. tissue specificity: Highly expressed in heart. Detected at lower levels in placenta and pancreas.
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