AffiAB® EP15R Rabbit Polyclonal Antibody

Specifications

Description

Function: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. PTM: Phosphorylated on tyrosine residues by EGFR. similarity: Contains 1 EF-hand domain. similarity: Contains 3 EH domains. subcellular location: Localized to plasma membrane coated pits. subunit: Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).