AffiAB® Anti-Mouse Anti-Chicken TCR γδ-FITC Conjugate Antibody

Specifications

Description

MAb TCR1 precipitates a heterodimer of Mr 90-kDa (two bands of Mr 40-kDa and 50-kDa upon reduction) on chicken peripheral blood T cells. eglycosylation of the heterodimer yields two polypeptides of Mr 35-kDa and 32-kDa from TCR1 precipitates. Unlike human and mouse, in which γδ cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of γδ T cells. The frequency of TCRγδ cells is usually 20-25% of the total blood T cells, but may reach approximately 50% in chickens of 6 months of age.